Graphene quantum dots rescue protein dysregulation of pancreatic β-cells exposed to human islet amyloid polypeptide

The amyloid aggregation of peptides and proteins is a hallmark of neurological disorders and type 2 diabetes. Human islet amyloid polypeptide (IAPP), co-secreted with insulin by pancreatic β-cells, plays dual roles in both glycemic control and the pathology of type 2 diabetes. While IAPP can activat...

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Vydáno v:Nano Res
Hlavní autoři: Faridi, Ava, Sun, Yunxiang, Mortimer, Monika, Aranha, Ritchlynn R., Nandakumar, Aparna, Li, Yuhuan, Javed, Ibrahim, Kakinen, Aleksandr, Fan, Qingqing, Purcell, Anthony W., Davis, Thomas P., Ding, Feng, Faridi, Pouya, Ke, Pu Chun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834229/
https://ncbi.nlm.nih.gov/pubmed/31695851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12274-019-2520-7
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