Structural basis of malaria RIFIN binding by LILRB1-containing antibodies

We previously reported that certain Plasmodium falciparum RIFINs, variant surface antigens expressed on infected erythrocytes(1), bind to the inhibitory receptor LAIR1 and insertions of DNA encoding LAIR1 into immunoglobulin genes generate RIFIN-specific antibodies(2,3). To address the general relev...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Nature
Autores principales: Chen, Yiwei, Xu, Kai, Piccoli, Luca, Foglierini, Mathilde, Tan, Joshua, Jin, Wenjie, Gorman, Jason, Tsybovsky, Yaroslav, Zhang, Baoshan, Traore, Boubacar, Silacci-Fregni, Chiara, Daubenberger, Claudia, Crompton, Peter D., Geiger, Roger, Sallusto, Federica, Kwong, Peter D., Lanzavecchia, Antonio
Formato: Artigo
Lenguaje:Inglês
Publicado: 2021
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8068667/
https://ncbi.nlm.nih.gov/pubmed/33790470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-021-03378-6
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares