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Public antibodies to malaria antigens generated by two LAIR1 insertion modalities
We previously described two donors in whom the extracellular domain of LAIR1, a collagen-binding inhibitory receptor encoded on chromosome 191, was inserted between the V and the DJ segments of an antibody. This insertion generated, through somatic mutations, broadly reactive antibodies against RIFI...
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Publicado no: | Nature |
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5635981/ https://ncbi.nlm.nih.gov/pubmed/28847005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature23670 |
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