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Do Memory CD4 T Cells Keep Their Cell-Type Programming: Plasticity versus Fate Commitment?: T-Cell Heterogeneity, Plasticity, and Selection in Humans

The wide range of effector and memory T cells is instrumental for immune regulation and tailored mechanisms of protection against pathogens. Here, we will focus on human CD4 T cells and discuss T-cell plasticity and intraclonal diversification in the context of a progressive and selective model of C...

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Detalles Bibliográficos
Publicado en:Cold Spring Harb Perspect Biol
Main Authors: Sallusto, Federica, Cassotta, Antonino, Hoces, Daniel, Foglierini, Mathilde, Lanzavecchia, Antonio
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830897/
https://ncbi.nlm.nih.gov/pubmed/28432133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a029421
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