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Do Memory CD4 T Cells Keep Their Cell-Type Programming: Plasticity versus Fate Commitment?: Complexities of Interpretation due to the Heterogeneity of Memory CD4 T Cells, Including T Follicular Helper Cells

Plasticity is the ability of a cell type to convert to another cell type. There are multiple effector CD4 T-cell subtypes, including T(H)1, T(H)2, T(H)17, T(H)1*, CD4 CTL, T(H)9, and T(FH) cells. It is commonly thought that a CD4 T cell can readily show full plasticity—full conversion from one diffe...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Biol
Autor principal: Crotty, Shane
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830898/
https://ncbi.nlm.nih.gov/pubmed/28432129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a032102
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