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Distinct memory CD4(+) T cells with commitment to T follicular helper- and T helper 1-cell lineages are generated after acute viral infection

CD4(+) T follicular helper (Tfh) cells provide the required signals to B cells for germinal center reactions that are necessary for long-lived antibody responses. However, it remains unclear whether there are CD4(+) memory T cells committed to the Tfh cell lineage after antigen clearance. Using adop...

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Detalhes bibliográficos
Main Authors: Hale, J. Scott, Youngblood, Ben, Latner, Donald R., Mohammed, Ata-Ur-Rasheed, Ye, Lilin, Akondy, Rama S., Wu, Tuoqi, Iyer, Smita S., Ahmed, Rafi
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741679/
https://ncbi.nlm.nih.gov/pubmed/23583644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.02.020
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