mTOR Promotes Antiviral Humoral Immunity by Differentially Regulating CD4 Helper T Cell and B Cell Responses

mTOR has important roles in regulation of both innate and adaptive immunity, but whether and how mTOR modulates humoral immune responses have yet to be fully understood. To address this issue, we examined the effects of rapamycin, a specific inhibitor of mTOR, on B cell and CD4 T cell responses duri...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Ye, Lilin, Lee, Junghwa, Xu, Lifan, Mohammed, Ata-Ur-Rasheed, Li, Weiyan, Hale, J. Scott, Tan, Wendy G., Wu, Tuoqi, Davis, Carl W., Ahmed, Rafi, Araki, Koichi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286878/
https://ncbi.nlm.nih.gov/pubmed/27974559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01653-16
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