mTOR Promotes Antiviral Humoral Immunity by Differentially Regulating CD4 Helper T Cell and B Cell Responses

mTOR has important roles in regulation of both innate and adaptive immunity, but whether and how mTOR modulates humoral immune responses have yet to be fully understood. To address this issue, we examined the effects of rapamycin, a specific inhibitor of mTOR, on B cell and CD4 T cell responses duri...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Ye, Lilin, Lee, Junghwa, Xu, Lifan, Mohammed, Ata-Ur-Rasheed, Li, Weiyan, Hale, J. Scott, Tan, Wendy G., Wu, Tuoqi, Davis, Carl W., Ahmed, Rafi, Araki, Koichi
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286878/
https://ncbi.nlm.nih.gov/pubmed/27974559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01653-16
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