mTOR Promotes Antiviral Humoral Immunity by Differentially Regulating CD4 Helper T Cell and B Cell Responses

mTOR has important roles in regulation of both innate and adaptive immunity, but whether and how mTOR modulates humoral immune responses have yet to be fully understood. To address this issue, we examined the effects of rapamycin, a specific inhibitor of mTOR, on B cell and CD4 T cell responses duri...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Ye, Lilin, Lee, Junghwa, Xu, Lifan, Mohammed, Ata-Ur-Rasheed, Li, Weiyan, Hale, J. Scott, Tan, Wendy G., Wu, Tuoqi, Davis, Carl W., Ahmed, Rafi, Araki, Koichi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2017
Onderwerpen:
Pathogenesis and Immunity
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286878/
https://ncbi.nlm.nih.gov/pubmed/27974559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01653-16
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