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The role of mTOR in memory CD8(+) T-cell differentiation

The mammalian target of rapamycin (mTOR) is an intracellular kinase that regulates cell growth and metabolism. Its specific inhibitor rapamycin is currently used in transplant recipients as an immunosuppressive drug to prevent allograft rejection. Studies have shown complex and diverse mechanisms fo...

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Detalhes bibliográficos
Main Authors: Araki, Koichi, Youngblood, Ben, Ahmed, Rafi
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760155/
https://ncbi.nlm.nih.gov/pubmed/20536567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.0105-2896.2010.00898.x
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