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The role of mTOR in memory CD8(+) T-cell differentiation

The mammalian target of rapamycin (mTOR) is an intracellular kinase that regulates cell growth and metabolism. Its specific inhibitor rapamycin is currently used in transplant recipients as an immunosuppressive drug to prevent allograft rejection. Studies have shown complex and diverse mechanisms fo...

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Bibliografiske detaljer
Main Authors: Araki, Koichi, Youngblood, Ben, Ahmed, Rafi
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760155/
https://ncbi.nlm.nih.gov/pubmed/20536567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.0105-2896.2010.00898.x
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