Binding and Action of Triphenylphosphonium Analog of Chloramphenicol upon the Bacterial Ribosome

Chloramphenicol (CHL) is a ribosome-targeting antibiotic that binds to the peptidyl transferase center (PTC) of the bacterial ribosome and inhibits peptide bond formation. As an approach for modifying and potentially improving the properties of this inhibitor, we explored ribosome binding and inhibi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Antibiotics (Basel)
Main Authors: Chen, Chih-Wei, Pavlova, Julia A., Lukianov, Dmitrii A., Tereshchenkov, Andrey G., Makarov, Gennady I., Khairullina, Zimfira Z., Tashlitsky, Vadim N., Paleskava, Alena, Konevega, Andrey L., Bogdanov, Alexey A., Osterman, Ilya A., Sumbatyan, Natalia V., Polikanov, Yury S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8066774/
https://ncbi.nlm.nih.gov/pubmed/33916420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics10040390
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados