Triphenilphosphonium Analogs of Chloramphenicol as Dual-Acting Antimicrobial and Antiproliferating Agents

In the current work, in continuation of our recent research, we synthesized and studied new chimeric compounds, including the ribosome-targeting antibiotic chloramphenicol (CHL) and the membrane-penetrating cation triphenylphosphonium (TPP), which are linked by alkyl groups of different lengths. Usi...

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發表在:Antibiotics (Basel)
Main Authors: Pavlova, Julia A., Khairullina, Zimfira Z., Tereshchenkov, Andrey G., Nazarov, Pavel A., Lukianov, Dmitrii A., Volynkina, Inna A., Skvortsov, Dmitry A., Makarov, Gennady I., Abad, Etna, Murayama, Somay Y., Kajiwara, Susumu, Paleskava, Alena, Konevega, Andrey L., Antonenko, Yuri N., Lyakhovich, Alex, Osterman, Ilya A., Bogdanov, Alexey A., Sumbatyan, Natalia V.
格式: Artigo
語言:Inglês
出版: MDPI 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145938/
https://ncbi.nlm.nih.gov/pubmed/33922611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics10050489
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