Triphenilphosphonium Analogs of Chloramphenicol as Dual-Acting Antimicrobial and Antiproliferating Agents

In the current work, in continuation of our recent research, we synthesized and studied new chimeric compounds, including the ribosome-targeting antibiotic chloramphenicol (CHL) and the membrane-penetrating cation triphenylphosphonium (TPP), which are linked by alkyl groups of different lengths. Usi...

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Библиографические подробности
Опубликовано в: :Antibiotics (Basel)
Главные авторы: Pavlova, Julia A., Khairullina, Zimfira Z., Tereshchenkov, Andrey G., Nazarov, Pavel A., Lukianov, Dmitrii A., Volynkina, Inna A., Skvortsov, Dmitry A., Makarov, Gennady I., Abad, Etna, Murayama, Somay Y., Kajiwara, Susumu, Paleskava, Alena, Konevega, Andrey L., Antonenko, Yuri N., Lyakhovich, Alex, Osterman, Ilya A., Bogdanov, Alexey A., Sumbatyan, Natalia V.
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2021
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145938/
https://ncbi.nlm.nih.gov/pubmed/33922611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics10050489
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