Triphenilphosphonium Analogs of Chloramphenicol as Dual-Acting Antimicrobial and Antiproliferating Agents

In the current work, in continuation of our recent research, we synthesized and studied new chimeric compounds, including the ribosome-targeting antibiotic chloramphenicol (CHL) and the membrane-penetrating cation triphenylphosphonium (TPP), which are linked by alkyl groups of different lengths. Usi...

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Vydáno v:Antibiotics (Basel)
Hlavní autoři: Pavlova, Julia A., Khairullina, Zimfira Z., Tereshchenkov, Andrey G., Nazarov, Pavel A., Lukianov, Dmitrii A., Volynkina, Inna A., Skvortsov, Dmitry A., Makarov, Gennady I., Abad, Etna, Murayama, Somay Y., Kajiwara, Susumu, Paleskava, Alena, Konevega, Andrey L., Antonenko, Yuri N., Lyakhovich, Alex, Osterman, Ilya A., Bogdanov, Alexey A., Sumbatyan, Natalia V.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145938/
https://ncbi.nlm.nih.gov/pubmed/33922611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics10050489
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