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Sir4 Deficiency Reverses Cell Senescence by Sub-Telomere Recombination
Telomere shortening results in cellular senescence and the regulatory mechanisms remain unclear. Here, we report that the sub-telomere regions facilitate telomere lengthening by homologous recombination, thereby attenuating senescence in yeast Saccharomyces cerevisiae. The telomere protein complex S...
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| Publicado no: | Cells |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8066019/ https://ncbi.nlm.nih.gov/pubmed/33915984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10040778 |
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