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Telomeric transcripts stimulate telomere recombination to suppress senescence in cells lacking telomerase
In human somatic cells or yeast cells lacking telomerase, telomeres are shortened upon each cell division. This gradual shortening of telomeres eventually leads to senescence. However, a small population of telomerase-deficient cells can survive by bypassing senescence through the activation of alte...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3948247/ https://ncbi.nlm.nih.gov/pubmed/24550456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307415111 |
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