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mRNA decay factor AUF1 maintains normal aging, telomere maintenance and suppression of senescence by activation of telomerase transcription
Inflammation is associated with DNA damage, cellular senescence and aging. Cessation of the inflammatory cytokine response is mediated in part through cytokine mRNA degradation facilitated by RNA binding proteins, including AUF1. We report a major unrecognized function of AUF1 – it activates telomer...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3966316/ https://ncbi.nlm.nih.gov/pubmed/22633954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.04.019 |
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