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Pif1 regulates telomere length by preferentially removing telomerase from long telomere ends
Telomerase, a ribonucleoprotein complex, is responsible for maintaining the telomere length at chromosome ends. Using its RNA component as a template, telomerase uses its reverse transcriptase activity to extend the 3′-end single-stranded, repetitive telomeric DNA sequence. Pif1, a 5′-to-3′ helicase...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4117769/ https://ncbi.nlm.nih.gov/pubmed/24981509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku541 |
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