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The Pif1 Helicase, a Negative Regulator of Telomerase, Acts Preferentially at Long Telomeres
Telomerase, the enzyme that maintains telomeres, preferentially lengthens short telomeres. The S. cerevisiae Pif1 DNA helicase inhibits both telomerase-mediated telomere lengthening and de novo telomere addition at double strand breaks (DSB). Here, we report that the association of the telomerase su...
Shranjeno v:
| izdano v: | PLoS Genet |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4408051/ https://ncbi.nlm.nih.gov/pubmed/25906395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005186 |
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