Nalaganje...

The Pif1 Helicase, a Negative Regulator of Telomerase, Acts Preferentially at Long Telomeres

Telomerase, the enzyme that maintains telomeres, preferentially lengthens short telomeres. The S. cerevisiae Pif1 DNA helicase inhibits both telomerase-mediated telomere lengthening and de novo telomere addition at double strand breaks (DSB). Here, we report that the association of the telomerase su...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Genet
Main Authors: Phillips, Jane A., Chan, Angela, Paeschke, Katrin, Zakian, Virginia A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408051/
https://ncbi.nlm.nih.gov/pubmed/25906395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005186
Oznake: Označite
Brez oznak, prvi označite!