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Roles of Telomere Biology in Cell Senescence, Replicative and Chronological Ageing

Telomeres with G-rich repetitive DNA and particular proteins as special heterochromatin structures at the termini of eukaryotic chromosomes are tightly maintained to safeguard genetic integrity and functionality. Telomerase as a specialized reverse transcriptase uses its intrinsic RNA template to le...

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Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Liu, Jun, Wang, Lihui, Wang, Zhiguo, Liu, Jun-Ping
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356700/
https://ncbi.nlm.nih.gov/pubmed/30650660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8010054
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