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Identification of peptidomimetic telomere dysfunction inhibitor (TELODIN) through telomere dysfunction-induced foci (TIF) assay

Telomere dysfunction-induced focus (TIF) assay allows efficient profiling of telomere dysfunctions in cells and tissues. Here, we describe the use of the TIF assay to screen synthetic peptides from E3 ubiquitin ligase FBW7, a tumor suppressor gene product, to prevent TIFs caused by environmental rad...

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Enregistré dans:
Détails bibliographiques
Publié dans:STAR Protoc
Auteurs principaux: Wang, Lihui, Wang, Zhiguo, Liu, Jun-Ping
Format: Artigo
Langue:Inglês
Publié: Elsevier 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233158/
https://ncbi.nlm.nih.gov/pubmed/34195674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100620
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