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TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence
Human telomerase reverse transcriptase (hTERT) plays a central role in telomere lengthening for continuous cell proliferation, but it remains unclear how extracellular cues regulate telomerase lengthening of telomeres. Here we report that the cytokine bone morphogenetic protein-7 (BMP7) induces the...
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| Publicado no: | Protein Cell |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Higher Education Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5233610/ https://ncbi.nlm.nih.gov/pubmed/27696331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-016-0322-1 |
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