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Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination
Mammalian telomeres have heterochromatic features, including trimethylated histone H3 at lysine 9 (H3K9me3) and trimethylated histone H4 at lysine 20 (H4K20me3). In addition, subtelomeric DNA is hypermethylated. The enzymatic activities responsible for these modifications at telomeres are beginning...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064618/ https://ncbi.nlm.nih.gov/pubmed/17846168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200703081 |
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