Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination

Mammalian telomeres have heterochromatic features, including trimethylated histone H3 at lysine 9 (H3K9me3) and trimethylated histone H4 at lysine 20 (H4K20me3). In addition, subtelomeric DNA is hypermethylated. The enzymatic activities responsible for these modifications at telomeres are beginning...

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Autores principales: Benetti, Roberta, Gonzalo, Susana, Jaco, Isabel, Schotta, Gunnar, Klatt, Peter, Jenuwein, Thomas, Blasco, María A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2007
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064618/
https://ncbi.nlm.nih.gov/pubmed/17846168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200703081
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