Altered telomere homeostasis and resistance to skin carcinogenesis in Suv39h1 transgenic mice

The Suv39h1 and Suv39h2 H3K9 histone methyltransferases (HMTs) have a conserved role in the formation of constitutive heterochromatin and gene silencing. Using a transgenic mouse model system we demonstrate that elevated expression of Suv39h1 increases global H3K9me3 levels in vivo. More specificall...

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Xehetasun bibliografikoak
Argitaratua izan da:Cell Cycle
Egile Nagusiak: Petti, Eleonora, Jordi, Fabian, Buemi, Valentina, Dinami, Roberto, Benetti, Roberta, Blasco, Maria A, Schoeftner, Stefan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2015
Gaiak:
Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614257/
https://ncbi.nlm.nih.gov/pubmed/25789788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1021517
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