Pulmonary Artery Smooth Muscle Cell Senescence Promotes the Proliferation of PASMCs by Paracrine IL-6 in Hypoxia-Induced Pulmonary Hypertension

Pulmonary hypertension (PH) is a critical and dangerous disease in cardiovascular system. Pulmonary vascular remodeling is an important pathophysiological mechanism for the development of pulmonary arterial hypertension. Pulmonary artery smooth muscle cell (PASMC) proliferation, hypertrophy, and enh...

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Dettagli Bibliografici
Pubblicato in:Front Physiol
Autori principali: Wang, Ai-Ping, Yang, Fang, Tian, Ying, Su, Jian-Hui, Gu, Qing, Chen, Wei, Gong, Shao-Xin, Ma, Xiao-Feng, Qin, Xu-Ping, Jiang, Zhi-Sheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058366/
https://ncbi.nlm.nih.gov/pubmed/33897463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.656139
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