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Thioredoxin-1 mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation
Pathological pulmonary artery smooth muscle cell (PASMC) proliferation contributes to pulmonary vascular remodeling in pulmonary hypertensive diseases associated with hypoxia. Both the hypoxia-inducible factor (HIF) and phosphatidylinositol 3-kinase (PI3K)/serine/threonine kinase (Akt) pathways have...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Physiological Society
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3763033/ https://ncbi.nlm.nih.gov/pubmed/23812635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00432.2012 |
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