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Thioredoxin-1 mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation

Pathological pulmonary artery smooth muscle cell (PASMC) proliferation contributes to pulmonary vascular remodeling in pulmonary hypertensive diseases associated with hypoxia. Both the hypoxia-inducible factor (HIF) and phosphatidylinositol 3-kinase (PI3K)/serine/threonine kinase (Akt) pathways have...

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Sonraí Bibleagrafaíochta
Main Authors: Chen, Bernadette, Nelin, Viktoria E., Locy, Morgan L., Jin, Yi, Tipple, Trent E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Physiological Society 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763033/
https://ncbi.nlm.nih.gov/pubmed/23812635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00432.2012
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