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Arginase II is a target of miR-17-5p and regulates miR-17-5p expression in human pulmonary artery smooth muscle cells

Vascular remodeling and smooth muscle cell proliferation are hallmark pathogenic features of pulmonary artery hypertension. MicroRNAs, endogenously expressed small noncoding RNAs, regulate gene expression at the posttranscriptional level. It has previously been shown that miR-17 overexpression in cu...

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Bibliografske podrobnosti
Main Authors: Jin, Youpeng, Jin, Yi, Chen, Bernadette, Tipple, Trent E., Nelin, Leif D.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152164/
https://ncbi.nlm.nih.gov/pubmed/24879052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00266.2013
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