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Arginase II is a target of miR-17-5p and regulates miR-17-5p expression in human pulmonary artery smooth muscle cells

Vascular remodeling and smooth muscle cell proliferation are hallmark pathogenic features of pulmonary artery hypertension. MicroRNAs, endogenously expressed small noncoding RNAs, regulate gene expression at the posttranscriptional level. It has previously been shown that miR-17 overexpression in cu...

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Bibliografiske detaljer
Main Authors: Jin, Youpeng, Jin, Yi, Chen, Bernadette, Tipple, Trent E., Nelin, Leif D.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152164/
https://ncbi.nlm.nih.gov/pubmed/24879052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00266.2013
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