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Arginase II is a target of miR-17-5p and regulates miR-17-5p expression in human pulmonary artery smooth muscle cells

Vascular remodeling and smooth muscle cell proliferation are hallmark pathogenic features of pulmonary artery hypertension. MicroRNAs, endogenously expressed small noncoding RNAs, regulate gene expression at the posttranscriptional level. It has previously been shown that miR-17 overexpression in cu...

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Autores principales: Jin, Youpeng, Jin, Yi, Chen, Bernadette, Tipple, Trent E., Nelin, Leif D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152164/
https://ncbi.nlm.nih.gov/pubmed/24879052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00266.2013
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