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Arginase II is a target of miR-17-5p and regulates miR-17-5p expression in human pulmonary artery smooth muscle cells

Vascular remodeling and smooth muscle cell proliferation are hallmark pathogenic features of pulmonary artery hypertension. MicroRNAs, endogenously expressed small noncoding RNAs, regulate gene expression at the posttranscriptional level. It has previously been shown that miR-17 overexpression in cu...

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Autors principals: Jin, Youpeng, Jin, Yi, Chen, Bernadette, Tipple, Trent E., Nelin, Leif D.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152164/
https://ncbi.nlm.nih.gov/pubmed/24879052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00266.2013
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