Role of hypoxia-induced transglutaminase 2 in pulmonary artery smooth muscle cell proliferation

We previously reported that transglutaminase 2 (TG2) activity is markedly elevated in lungs of hypoxia-exposed rodent models of pulmonary hypertension (PH). Since vascular remodeling of pulmonary artery smooth muscle cells (PASMCs) is important in PH, we undertook the present study to determine whet...

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Main Authors: Penumatsa, Krishna C., Toksoz, Deniz, Warburton, Rod R., Hilmer, Andrew J., Liu, Tiegang, Khosla, Chaitan, Comhair, Suzy A. A., Fanburg, Barry L.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2014
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187037/
https://ncbi.nlm.nih.gov/pubmed/25128524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00162.2014
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