Elevated Transglutaminase 2 Activity is Associated with Hypoxia-Induced Experimental Pulmonary Hypertension in Mice

Previous studies in human patients and animal models have suggested that transglutaminase 2 (TG2) is upregulated in pulmonary hypertension (PH), a phenomenon that appears to be associated with the effects of serotonin (5-hydroxytryptamine; 5-HT) in this disease. Using chemical tools to interrogate a...

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Bibliographic Details
Main Authors: DiRaimondo, Thomas R., Klock, Cornelius, Warburton, Rod, Herrera, Zachary, Penumatsa, Krishna, Toksoz, Deniz, Hill, Nicholas, Khosla, Chaitan, Fanburg, Barry
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947056/
https://ncbi.nlm.nih.gov/pubmed/24152195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb4006408
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