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Activation of the Sonic Hedgehog Signaling Controls Human Pulmonary Arterial Smooth Muscle Cell Proliferation in Response to Hypoxia

The hedgehog signal pathway plays a crucial role in the angiogenesis and vascular remodeling. However, the function of this pathway in the pulmonary vascular smooth cell proliferation in response to hypoxia remains unknown. In this study, we have demonstrated that the main components of the hedgehog...

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Detalhes bibliográficos
Main Authors: Wang, Guansong, Zhang, Zhiyuan, Xu, Zhi, Yin, Hongjin, Bai, Li, Ma, Zhuang, DeCoster, Mark A., Qian, Guisheng, Wu, Guangyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956789/
https://ncbi.nlm.nih.gov/pubmed/20840857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2010.09.002
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