Pulmonary Artery Smooth Muscle Cell Senescence Promotes the Proliferation of PASMCs by Paracrine IL-6 in Hypoxia-Induced Pulmonary Hypertension

Pulmonary hypertension (PH) is a critical and dangerous disease in cardiovascular system. Pulmonary vascular remodeling is an important pathophysiological mechanism for the development of pulmonary arterial hypertension. Pulmonary artery smooth muscle cell (PASMC) proliferation, hypertrophy, and enh...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Wang, Ai-Ping, Yang, Fang, Tian, Ying, Su, Jian-Hui, Gu, Qing, Chen, Wei, Gong, Shao-Xin, Ma, Xiao-Feng, Qin, Xu-Ping, Jiang, Zhi-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058366/
https://ncbi.nlm.nih.gov/pubmed/33897463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.656139
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