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1,2-Naphthoquinone as a Poison of Human Type II Topoisomerases

1,2-Naphthoquinone, a secondary metabolite of naphthalene, is an environmental pollutant found in diesel exhaust particles that displays cytotoxic and genotoxic properties. Because many quinones have been shown to act as topoisomerase II poisons, the effects of this compound on DNA cleavage mediated...

詳細記述

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書誌詳細
出版年:Chem Res Toxicol
主要な著者: Collins, Jessica A., Osheroff, Neil
フォーマット: Artigo
言語:Inglês
出版事項: 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058326/
https://ncbi.nlm.nih.gov/pubmed/33760604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.0c00492
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