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Cysteine-based crosslinking approach for characterization of oligomeric pore-forming proteins in the mitochondrial membranes

Mitochondria are important not only to healthy but also dying cells. In particular, apoptotic cell death initiates when the mitochondrial outer membrane is permeabilized by Bax, a protein of the Bcl-2 family. Bax shares a structural fold with some α-helical bacterial pore-forming toxins before these...

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Publicado en:Methods Enzymol
Main Authors: Zhang, Zhi, Huang, Bo, Zhang, Xuejun C., Lin, Jialing
Formato: Artigo
Idioma:Inglês
Publicado: 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055231/
https://ncbi.nlm.nih.gov/pubmed/33712193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2021.01.023
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