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Cysteine-based crosslinking approach for characterization of oligomeric pore-forming proteins in the mitochondrial membranes
Mitochondria are important not only to healthy but also dying cells. In particular, apoptotic cell death initiates when the mitochondrial outer membrane is permeabilized by Bax, a protein of the Bcl-2 family. Bax shares a structural fold with some α-helical bacterial pore-forming toxins before these...
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| Veröffentlicht in: | Methods Enzymol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8055231/ https://ncbi.nlm.nih.gov/pubmed/33712193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2021.01.023 |
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