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Cysteine-based crosslinking approach for characterization of oligomeric pore-forming proteins in the mitochondrial membranes

Mitochondria are important not only to healthy but also dying cells. In particular, apoptotic cell death initiates when the mitochondrial outer membrane is permeabilized by Bax, a protein of the Bcl-2 family. Bax shares a structural fold with some α-helical bacterial pore-forming toxins before these...

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Bibliografische gegevens
Gepubliceerd in:Methods Enzymol
Hoofdauteurs: Zhang, Zhi, Huang, Bo, Zhang, Xuejun C., Lin, Jialing
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055231/
https://ncbi.nlm.nih.gov/pubmed/33712193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2021.01.023
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