An amphipathic Bax core dimer forms part of the apoptotic pore wall in the mitochondrial␣membrane

Bax proteins form pores in the mitochondrial outer membrane to initiate apoptosis. This might involve their embedding in the cytosolic leaflet of the lipid bilayer, thus generating tension to induce a lipid pore with radially arranged lipids forming the wall. Alternatively, Bax proteins might compri...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Lv, Fujiao, Qi, Fei, Zhang, Zhi, Wen, Maorong, Kale, Justin, Piai, Alessandro, Du, Lingyu, Wang, Shuqing, Zhou, Liujuan, Yang, Yaqing, Wu, Bin, Liu, Zhijun, del Rosario, Juan, Pogmore, Justin, Chou, James J, Andrews, David W, Lin, Jialing, OuYang, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280806/
https://ncbi.nlm.nih.gov/pubmed/34101209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106438
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