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Bax assembly into rings and arcs in apoptotic mitochondria is linked to membrane pores
Bax is a key regulator of apoptosis that, under cell stress, accumulates at mitochondria, where it oligomerizes to mediate the permeabilization of the mitochondrial outer membrane leading to cytochrome c release and cell death. However, the underlying mechanism behind Bax function remains poorly und...
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| Udgivet i: | EMBO J |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4755116/ https://ncbi.nlm.nih.gov/pubmed/26783362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593384 |
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