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MIM through MOM: the awakening of Bax and Bak pores

The mechanism whereby mitochondrial DNA (mtDNA) is released into the cytosol and activates the cGAS/STING inflammatory pathway during Bax/Bax‐mediated apoptosis is unknown. In this issue, Riley et al (2018) report that widening of Bax and Bak pores on the mitochondrial outer membrane (MOM) during ap...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Cosentino, Katia, García‐Sáez, Ana J
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120657/
https://ncbi.nlm.nih.gov/pubmed/30135068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100340
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