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Proapoptotic Bax and Bak Proteins Form Stable Protein-permeable Pores of Tunable Size

The Bcl-2 proapoptotic proteins Bax and Bak mediate the permeabilization of the mitochondrial outer membrane during apoptosis. Current models consider that Bax and Bak form pores at the mitochondrial outer membrane that are responsible for the release of cytochrome c and other larger mitochondrial a...

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Bibliografische gegevens
Hoofdauteurs: Bleicken, Stephanie, Landeta, Olatz, Landajuela, Ane, Basañez, Gorka, García-Sáez, Ana J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829170/
https://ncbi.nlm.nih.gov/pubmed/24100034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.512087
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