REST Protects Dopaminergic Neurons from Mitochondrial and α-Synuclein Oligomer Pathology in an Alpha Synuclein Overexpressing BAC-Transgenic Mouse Model

Alpha-synuclein pathology is associated with dopaminergic neuronal loss in the substantia nigra (SN) of Parkinson's patients. Working across human and mouse models, we investigated mechanisms by which the accumulation of soluble α-synuclein oligomers leads to neurodegeneration. Biochemical anal...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Ryan, Brent J., Bengoa-Vergniory, Nora, Williamson, Matthew, Kirkiz, Ecem, Roberts, Rosalind, Corda, Gabriele, Sloan, Maximilian, Saqlain, Saba, Cherubini, Marta, Poppinga, Josse, Bogtofte, Helle, Cioroch, Milena, Hester, Svenja, Wade-Martins, Richard
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2021
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055072/
https://ncbi.nlm.nih.gov/pubmed/33563726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1478-20.2021
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker