Oxidative post-translational modifications and their involvement in the pathogenesis of autoimmune diseases

Por Ryan, Brent J., Nissim, Ahuva, Winyard, Paul G.
Publicado em 2014

Commentary: Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models

Por Fernandes, Hugo J. R., Ryan, Brent J., Wade-Martins, Richard
Publicado no Front Neurosci (2016)

Protein-protein interaction networks identify targets which rescue the MPP(+) cellular model of Parkinson’s disease

Por Keane, Harriet, Ryan, Brent J., Jackson, Brendan, Whitmore, Alan, Wade-Martins, Richard
Publicado no Sci Rep (2015)

α-Synuclein and mitochondrial bioenergetics regulate tetrahydrobiopterin levels in a human dopaminergic model of Parkinson disease

Por Ryan, Brent J., Lourenço-Venda, Lara L., Crabtree, Mark J., Hale, Ashley B., Channon, Keith M., Wade-Martins, Richard
Publicado no Free Radic Biol Med (2013)

Autoantibodies to Posttranslational Modifications in Rheumatoid Arthritis

Por Burska, Agata N., Hunt, Laura, Boissinot, Marjorie, Strollo, Rocky, Ryan, Brent J., Vital, Ed, Nissim, Ahuva, Winyard, Paul G., Emery, Paul, Ponchel, Frederique
Publicado em 2014

A novel role for endothelial tetrahydrobiopterin in mitochondrial redox balance

Por Bailey, Jade, Shaw, Andrew, Fischer, Roman, Ryan, Brent J., Kessler, Benedikt M., McCullagh, James, Wade-Martins, Richard, Channon, Keith M., Crabtree, Mark J.
Publicado no Free Radic Biol Med (2017)

A requirement for Gch1 and tetrahydrobiopterin in embryonic development

Por Douglas, Gillian, Hale, Ashley B., Crabtree, Mark J, Ryan, Brent J., Hansler, Alex, Watschinger, Katrin, Gross, Steven S, Lygate, Craig A., Alp, Nicholas J., Channon, Keith M.
Publicado no Dev Biol (2015)

ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons

Por Fernandes, Hugo J.R., Hartfield, Elizabeth M., Christian, Helen C., Emmanoulidou, Evangelia, Zheng, Ying, Booth, Heather, Bogetofte, Helle, Lang, Charmaine, Ryan, Brent J., Sardi, S. Pablo, Badger, Jennifer, Vowles, Jane, Evetts, Samuel, Tofaris, George K., Vekrellis, Kostas, Talbot, Kevin, Hu, Michele T., James, William, Cowley, Sally A., Wade-Martins, Richard
Publicado no Stem Cell Reports (2016)