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A novel role for endothelial tetrahydrobiopterin in mitochondrial redox balance
The redox co-factor tetrahydrobiopterin (BH(4)) regulates nitric oxide (NO) and reactive oxygen species (ROS) production by endothelial NOS (eNOS) and is an important redox-dependent signalling molecule in the endothelium. Loss of endothelial BH(4) is observed in cardiovascular disease (CVD) states...
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| Publicado no: | Free Radic Biol Med |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338462/ https://ncbi.nlm.nih.gov/pubmed/28104455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.01.012 |
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