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Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease

Nitric oxide, generated by the nitric oxide synthase (NOS) enzymes, plays pivotal roles in cardiovascular homeostasis and in the pathogenesis of cardiovascular disease. The NOS cofactor, tetrahydrobiopterin (BH4), is an important regulator of NOS function, since BH4 is required to maintain enzymatic...

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Detalhes bibliográficos
Publicado no:Nitric Oxide
Main Authors: Crabtree, Mark J., Channon, Keith M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357050/
https://ncbi.nlm.nih.gov/pubmed/21550412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2011.04.004
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