A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats

Conversion of soluble α-synuclein into insoluble and fibrillar inclusions is a hallmark of Parkinson’s disease and other synucleinopathies. Accumulating evidence points towards a relationship between its generation at nerve terminals and structural synaptic pathology. Little is known about the patho...

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Detalhes bibliográficos
Principais autores: Nuber, Silke, Harmuth, Florian, Kohl, Zacharias, Adame, Anthony, Trejo, Margaritha, Schönig, Kai, Zimmermann, Frank, Bauer, Claudia, Casadei, Nicolas, Giel, Christiane, Calaminus, Carsten, Pichler, Bernd J., Jensen, Poul H., Müller, Christian P., Amato, Davide, Kornhuber, Johannes, Teismann, Peter, Yamakado, Hodaka, Takahashi, Ryosuke, Winkler, Juergen, Masliah, Eliezer, Riess, Olaf
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572936/
https://ncbi.nlm.nih.gov/pubmed/23413261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aws358
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