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A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats
Conversion of soluble α-synuclein into insoluble and fibrillar inclusions is a hallmark of Parkinson’s disease and other synucleinopathies. Accumulating evidence points towards a relationship between its generation at nerve terminals and structural synaptic pathology. Little is known about the patho...
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| Hlavní autoři: | , , , , , , , , , , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3572936/ https://ncbi.nlm.nih.gov/pubmed/23413261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aws358 |
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