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Intracellular A53T Mutant α-Synuclein Impairs Adult Hippocampal Newborn Neuron Integration

Dendritic dysfunction is an early event in α-synuclein (α-syn) mediated neurodegeneration. Altered postsynaptic potential and loss of dendritic spines have been observed in different in vitro and in vivo models of synucleinopathies. The integration of newborn neurons into the hippocampus offers the...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Regensburger, Martin, Stemick, Judith, Masliah, Eliezer, Kohl, Zacharias, Winner, Beate
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686440/
https://ncbi.nlm.nih.gov/pubmed/33262984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.561963
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