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Intracellular A53T Mutant α-Synuclein Impairs Adult Hippocampal Newborn Neuron Integration
Dendritic dysfunction is an early event in α-synuclein (α-syn) mediated neurodegeneration. Altered postsynaptic potential and loss of dendritic spines have been observed in different in vitro and in vivo models of synucleinopathies. The integration of newborn neurons into the hippocampus offers the...
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| Publicado no: | Front Cell Dev Biol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7686440/ https://ncbi.nlm.nih.gov/pubmed/33262984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.561963 |
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