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β–Synuclein occurs in vivo in lipid associated oligomers and forms hetero oligomers with α-synuclein

α-synuclein (αS) and β-synuclein (βS) are homologous proteins implicated in Parkinson’s disease and the related synucleinopathies. While αS is neurotoxic and its aggregation and deposition in Lewy bodies is related to neurodegeneration, βS is considered a potent inhibitor of αS aggregation and toxic...

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Bibliografiske detaljer
Main Authors: Israeli, Eitan, Sharon, Ronit
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832289/
https://ncbi.nlm.nih.gov/pubmed/19012742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05776.x
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