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In vivo demonstration that α-synuclein oligomers are toxic
The aggregation of proteins into oligomers and amyloid fibrils is characteristic of several neurodegenerative diseases, including Parkinson disease (PD). In PD, the process of aggregation of α-synuclein (α-syn) from monomers, via oligomeric intermediates, into amyloid fibrils is considered the disea...
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| Autors principals: | , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3053976/ https://ncbi.nlm.nih.gov/pubmed/21325059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100976108 |
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