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The fold of α-synuclein fibrils

The aggregation of proteins into amyloid fibrils is associated with several neurodegenerative diseases. In Parkinson's disease it is believed that the aggregation of α-synuclein (α-syn) from monomers by intermediates into amyloid fibrils is the toxic disease-causative mechanism. Here, we studie...

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Main Authors: Vilar, Marçal, Chou, Hui-Ting, Lührs, Thorsten, Maji, Samir K., Riek-Loher, Dominique, Verel, Rene, Manning, Gerard, Stahlberg, Henning, Riek, Roland
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438424/
https://ncbi.nlm.nih.gov/pubmed/18550842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712179105
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